Setshaba HIV Prevention and Care Unit
Official title: PHRU-Setshaba Clinical Trials Unit
Funded at Wits Health Consortium (Pty), LTD · NIH-11238872 · Data updated 2026-11-12
A Parktown-based research unit working with children and adults at risk for or living with HIV to test new prevention, treatment, and remission approaches, including care for TB co-infection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wits Health Consortium (Pty), LTD NIH-funded |
| Lab location | 1 site (Parktown, South Africa) |
| Project start | February 15, 2007 |
| Project end | November 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $2,656,657 |
| NIH project number | 5UM1AI069453-20 |
| Project ID | NIH-11238872 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults and children living with HIV, people at high risk of acquiring HIV, pregnant people, and individuals with TB/HIV co‑infection in the unit’s catchment areas are the typical candidates.
✕Less likely to help
People with no HIV risk or those who cannot travel to the Parktown area are unlikely to be eligible or receive direct benefit from this unit’s work.
What this research studies
If you take part, you would work with clinical teams at one of seven local research sites in high‑HIV areas around Parktown, including clinics, maternity units, and TB clinics. The unit enrolls children and adults, collects health information and laboratory samples, and follows participants over time while offering standard-of-care services. Studies include testing vaccines, prevention tools, treatment strategies, and research on HIV remission and TB/HIV interactions. Participation may involve regular visits, blood draws, and adherence or symptom monitoring depending on the specific project.
Why it matters
Potential benefit: Successful work here could lead to better ways to prevent HIV, improve long‑term treatment, and manage TB co‑infection for people in the region.
How similar studies have gone: Previous NIH‑supported HIV prevention and treatment trials have produced effective ARV strategies and prevention tools, though vaccine and remission research remains challenging and ongoing.
Where this research is happening
-
Wits Health Consortium (Pty), LTD
Parktown, South Africa Active
Researchers
- Principal investigator: Gray, Glenda E — Wits Health Consortium (Pty), LTD
- Study coordinator: Gray, Glenda E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.