Sensitive, child-friendly brain sensors to record fast brain waves in infants

Closed-Loop Triaxial Optically Pumped Magnetometers for High-Sensitivity and High-Bandwidth Magnetoencephalography Measurements of the Developing Brain

NIH-funded research Sandia Corp-Sandia National Laboratories · NIH-11160527

We are building very sensitive, child-friendly brain sensors to record fast, tiny brain waves in six-month-old infants to better understand early brain development and conditions like autism or neurodegenerative disorders.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionSandia Corp-Sandia National Laboratories NIH-funded
Lab location1 site (Albuquerque, United States)
Project IDNIH-11160527 on NIH RePORTER

What this research studies

You or your infant would help develop a new kind of non-invasive brain scanner (MEG) that uses tiny light-based magnetic sensors called optically pumped magnetometers (OPMs). The team is working with an industry partner to create triaxial, closed-loop OPMs with much higher sensitivity and faster bandwidth so they can pick up high-frequency 'gamma' brain waves near the scalp. The sensors are designed to be adjustable for each head and to reject outside interference, so recordings from six-month-old infants are clearer. If the sensors work as planned, researchers will use short, in-person recordings while infants hear sounds or do simple tasks to map early brain activity patterns.

Who could benefit from this research

Good fit: Ideal participants are infants around six months old whose families can travel to a participating lab for short, non-invasive brain recordings.

Not a fit: Adults, children outside the infant age window, or anyone unable to come to a lab or tolerate the recording would not be eligible to participate or likely benefit directly.

Why it matters

Potential benefit: If successful, this could let researchers detect early changes in infant brain activity, helping to spot developmental or degenerative conditions sooner and guide better interventions.

How similar studies have performed: MEG and earlier OPM sensors have been used in adults and older children, but using triaxial closed-loop OPMs to reliably record high-frequency gamma activity in six-month-old infants is new and largely untested.

Where this research is happening

Albuquerque, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Degenerative Neurologic Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.