Self-management program to lower stroke risk in Ugandans
Official title: A Targeted Self-Management Intervention for Reducing Stroke Risk Factors in High Risk Ugandans
Funded at Case Western Reserve University · NIH-10875532 · Data updated 2026-11-12
This project teaches high-risk Ugandans practical self-care skills to lower blood pressure, improve cholesterol, and reduce stroke risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Case Western Reserve University NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | September 1, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $574,743 |
| NIH project number | 5R01NS118544-05 |
| Project ID | NIH-10875532 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults in Uganda at high risk for stroke, for example people with hypertension, diabetes, high cholesterol, or other vascular risk factors, are the intended participants.
✕Less likely to help
People without vascular risk factors, those living outside the participating Ugandan clinics, or individuals with severe disability from a recent major stroke may not benefit from this preventive program.
What this research studies
If I join, I would follow a curriculum-guided program called TEAM that teaches lifestyle changes and ways to manage stroke risk factors like high blood pressure, diabetes, and cholesterol. The program was developed after pilot work and uses low-cost, practical strategies designed to be acceptable and scalable in Ugandan communities. Program staff will track things like blood pressure and blood test results to see if risk markers improve over time. The approach focuses on group education, self-management skills, and ongoing support rather than expensive medicines or equipment.
Why it matters
Potential benefit: If successful, this could help participants lower blood pressure and cholesterol and reduce their chance of having a stroke, and it could be spread more widely across Uganda.
How similar studies have gone: A small pilot showed high retention and improvements in blood pressure and lipids, but larger trials are still needed to confirm broad effectiveness.
Where this research is happening
-
Case Western Reserve University
Cleveland, United States Active
Researchers
- Principal investigator: Sajatovic, Martha X — Case Western Reserve University
- Study coordinator: Sajatovic, Martha X
Related research
Other NIH-funded projects on the same topics.
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A program to help high-risk Ugandans manage their stroke risk factors
This study is testing a new program called TEAM to help people in Uganda who are at high risk for strokes by teaching them easy and affordable ways to manage their health, like improving their diet and controlling conditions like high blood pressure and diabetes.
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Improving Participation after Stroke: Self-Management Rehab for Sub-Acute Stroke
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Improving brain health and reducing stroke risk through cognitive training and coaching.
This study is testing an online program that helps stroke survivors and their family members boost brain function and manage health risks together, making it easier for everyone to stay healthy and support each other.
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Virtual program to help stroke survivors get back to home, work, and community activities
This project offers a virtual self-management program for people recovering from a recent stroke to boost confidence, daily activity, and community participation.
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Understanding What Causes Stroke in Women
This project looks at many different proteins in women to understand what might lead to a stroke.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.