Self-management program to lower stroke risk in Ugandans

A Targeted Self-Management Intervention for Reducing Stroke Risk Factors in High Risk Ugandans

NIH-funded research Case Western Reserve University · NIH-10875532

This project teaches high-risk Ugandans practical self-care skills to lower blood pressure, improve cholesterol, and reduce stroke risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-10875532 on NIH RePORTER

What this research studies

If I join, I would follow a curriculum-guided program called TEAM that teaches lifestyle changes and ways to manage stroke risk factors like high blood pressure, diabetes, and cholesterol. The program was developed after pilot work and uses low-cost, practical strategies designed to be acceptable and scalable in Ugandan communities. Program staff will track things like blood pressure and blood test results to see if risk markers improve over time. The approach focuses on group education, self-management skills, and ongoing support rather than expensive medicines or equipment.

Who could benefit from this research

Good fit: Adults in Uganda at high risk for stroke, for example people with hypertension, diabetes, high cholesterol, or other vascular risk factors, are the intended participants.

Not a fit: People without vascular risk factors, those living outside the participating Ugandan clinics, or individuals with severe disability from a recent major stroke may not benefit from this preventive program.

Why it matters

Potential benefit: If successful, this could help participants lower blood pressure and cholesterol and reduce their chance of having a stroke, and it could be spread more widely across Uganda.

How similar studies have performed: A small pilot showed high retention and improvements in blood pressure and lipids, but larger trials are still needed to confirm broad effectiveness.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.