Selective targeting approaches for pancreatic cancer
Selective Targeting of Pancreatic Cancer SPORE
New targeted therapies and better tests are being developed for people with pancreatic cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11196730 on NIH RePORTER |
What this research studies
This program brings together laboratory and clinic teams to discover treatments and biomarkers for pancreatic cancer. Researchers will study tumor and blood samples to understand tumor genetics, the fibrous stroma, and immune suppression that block current therapies. The work combines lab experiments, analysis of patient-derived samples, and early-phase clinical trials that may enroll patients and collect tissue and blood. Multiple parallel projects aim to move promising lab findings quickly into patient testing.
Who could benefit from this research
Good fit: People diagnosed with pancreatic cancer, especially those with advanced disease or who can provide tumor or blood samples, may be eligible to participate.
Not a fit: People without pancreatic cancer or those who cannot travel to a research site or do not meet trial eligibility requirements are unlikely to benefit directly from this program.
Why it matters
Potential benefit: If successful, this work could lead to more personalized treatments, improved tests to match patients with the right therapies, and longer survival for people with pancreatic cancer.
How similar studies have performed: Some targeted and immune-based approaches have shown promise in other cancers and in early pancreatic trials, but pancreatic cancer remains challenging so this program combines both tested and novel strategies.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Yeh, Jen Jen — Univ of North Carolina Chapel Hill
- Study coordinator: Yeh, Jen Jen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.