Secure data platform to track health and treatment outcomes for adults with HIV in North America and Europe
Official title: A secure analytics platform to study the prognosis of people with HIV in the USA, Canada and Europe and comparative effectiveness of treatment regimens: the Antiretroviral Therapy Cohort Collaboration
Funded at University of Bristol · NIH-11163470 · Data updated 2026-11-12
This project builds a secure online system that lets researchers analyze health and treatment outcomes for adults living with HIV in the US, Canada, and Europe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Bristol NIH-funded |
| Lab location | 1 site (Bristol, United Kingdom) |
| Project start | August 7, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $483,540 |
| NIH project number | 5R01AI181733-02 |
| Project ID | NIH-11163470 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who are receiving antiretroviral therapy and are enrolled in one of the participating North American or European cohort sites are the most relevant contributors or candidates for inclusion.
✕Less likely to help
Children, adolescents under the adult age cutoff, people not on ART, or those living outside the participating regions are unlikely to be included or to benefit directly from this project.
What this research studies
I am living with HIV and this project combines information from 20 clinical cohorts covering about 250,000 people on antiretroviral therapy to update prognosis and compare modern treatment regimens. The team will create a secure, privacy-protecting platform that holds pseudonymized data and lets approved researchers run shared, reproducible analysis code without moving raw data. Any results exported from the platform must pass review by trained output checkers to protect participant privacy. This approach aims to speed collaborative research across North America and Europe while keeping my data safer.
Why it matters
Potential benefit: If successful, this could give clinicians and patients clearer, up-to-date information about expected health outcomes and which ART regimens work best in real-world settings.
How similar studies have gone: This builds on the established Antiretroviral Therapy Cohort Collaboration, which has previously classified causes of death and produced influential insights from large pooled HIV cohorts.
Where this research is happening
-
University of Bristol
Bristol, United Kingdom Active
Researchers
- Principal investigator: Sterne, Jonathan — University of Bristol
- Study coordinator: Sterne, Jonathan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.