Screening for syphilis in emergency departments to help vulnerable populations

Implementation of emergency department screening to impact rising syphilis rates in vulnerable populations

NIH-funded research University of Chicago · NIH-10889206

This study is testing a new way to screen for syphilis in emergency rooms to help people, especially women who could become pregnant, get the care they need, and reduce the number of syphilis cases in our communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10889206 on NIH RePORTER

What this research studies

This research aims to implement universal syphilis screening in emergency departments, targeting vulnerable populations who may not seek routine outpatient care. By identifying syphilis cases among patients, especially women of childbearing potential, the project seeks to reduce the rising rates of syphilis and congenital syphilis. The approach involves pilot-testing a new screening method in the emergency department, where many at-risk individuals seek medical help. The ultimate goal is to create a scalable model that can be applied in urban emergency departments across the country.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals visiting emergency departments, particularly those from minority populations and women of childbearing age.

Not a fit: Patients who are not at risk for syphilis or those who do not visit emergency departments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce syphilis rates and prevent congenital syphilis in infants.

How similar studies have performed: Other research has shown success with similar screening approaches in emergency settings, indicating potential for effective implementation.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.