Screening for developmental delays in children with sickle cell disease
Official title: (SCANS) Sickle Cell Anemia Neurodevelopmental Screening - Mentoring and Research in Patient Oriented Research
Funded at Washington University · NIH-10685968 · Data updated 2026-11-12
This study is looking at how sickle cell disease can affect the development and thinking skills of young children, so we can help kids aged 0-11 get the support they need early on to do better in school.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project start | September 20, 2019 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $109,455 |
| NIH project number | 5K24HL148305-05 |
| Project ID | NIH-10685968 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 diagnosed with sickle cell disease.
✕Less likely to help
Patients outside the age range of 0-11 or those without a diagnosis of sickle cell disease may not benefit from this research.
What this research studies
This research focuses on identifying developmental delays and cognitive impairments in young children with sickle cell disease (SCD), a condition often overlooked in routine screenings. The project aims to implement developmental screening processes to ensure that children receive necessary interventions early in life, which can significantly improve their educational outcomes. A multidisciplinary team, including hematologists and neuropsychologists, will work together to assess and address these developmental needs. By targeting children aged 0-11, the research seeks to provide evidence-based resources to support their growth and academic success.
Why it matters
Potential benefit: If successful, this research could lead to improved developmental outcomes and academic success for children with sickle cell disease.
How similar studies have gone: Previous research has shown success in implementing developmental screenings in similar pediatric populations, indicating a promising approach.
Where this research is happening
-
Washington University
Saint Louis, United States Active
Researchers
- Principal investigator: King, Allison a — Washington University
- Study coordinator: King, Allison a
Related research
Other NIH-funded projects on the same topics.
-
Hydroxyurea to help children with sickle cell anemia in Africa
A pediatric study tests hydroxyurea treatment for young children with sickle cell anemia in several African countries to see if it can reduce illness and improve health.
-
Hydroxyurea for Children with Sickle Cell in Africa
A pilot study tests hydroxyurea in young children with sickle cell disease across several African countries to see if it can reduce illness and hospital visits.
-
Hydroxyurea for Children with Sickle Cell Disease in Africa
A safe and feasible use of hydroxyurea for young children with sickle cell disease in several African countries to reduce illness and improve daily life.
-
Hypoxemia during Sleep in Sickle Cell Disease: How Common is It and How Might Treatments Help
This study looks at how low oxygen during sleep affects adults with sickle cell disease and how they respond to therapy across multiple urban and rural sites.
-
Hypoxic red blood cells for sickle cell anemia using the Hemanext ONE system
A new approach using special low-oxygen red blood cells from the Hemanext ONE system is being tested to help adults and children with sickle cell anemia who rely on frequent transfusions.
-
Hydroxyurea for Children with Sickle Cell Anemia in Africa
A safety and feasibility pilot study tests giving hydroxyurea to young children with sickle cell anemia in sub-Saharan Africa to reduce illness and death.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.