Screening and monitoring for HPV-related throat cancer using remote self-sampling
Official title: HPV-related Oropharyngeal Cancer Screening and Monitoring through Remote Self-Sampling
Funded at Baylor College of Medicine · NIH-11077291 · Data updated 2026-11-12
This study is looking at how well people can use simple, at-home methods to check for HPV-related throat cancer, especially for those who might not have easy access to doctors, and it compares these methods to the usual tests done in clinics.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | April 19, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $678,031 |
| NIH project number | 5U01DE032997-02 |
| Project ID | NIH-11077291 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals over 21 years old, particularly those at risk for HPV-related cancers or with limited access to healthcare.
✕Less likely to help
Patients who are not at risk for HPV-related cancers or those who have already been diagnosed and are receiving treatment may not benefit from this research.
What this research studies
This research investigates the use of non-invasive self-sampling methods to screen for and monitor HPV-related oropharyngeal cancer (OPC). It aims to evaluate the effectiveness and acceptance of these self-collected samples compared to traditional clinic-based methods. The study focuses on utilizing blood-based biomarkers to identify the presence of HPV and its potential link to cancer risk, particularly in populations with limited access to healthcare. By extending the research beyond clinical trials, it seeks to include a broader demographic, including women and those with less access to medical facilities.
Why it matters
Potential benefit: If successful, this research could provide a more accessible and effective method for early detection of HPV-related throat cancer, potentially improving patient outcomes.
How similar studies have gone: Previous research has shown promise in using self-sampling methods for cancer screening, indicating that this approach could be effective and beneficial.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Sturgis, Erich Madison — Baylor College of Medicine
- Study coordinator: Sturgis, Erich Madison
Related research
Other NIH-funded projects on the same topics.
-
AI-powered predictor for chemoradiation response in Veterans with oropharyngeal cancer
A new AI-based tool will help doctors tailor chemoradiation for Veterans with oropharyngeal cancer by predicting how each patient will respond to treatment.
-
OPC Survivor: Optimizing Long-Term Health After Oropharyngeal Cancer
This program studies how to improve long-term health and quality of life for adults treated for HPV-related oropharyngeal cancer.
-
Optimizing HPV-positive oropharyngeal cancer treatment by selecting patients and reducing therapy intensity
This grant explores whether we can choose the right patients with HPV-positive throat cancer for less intensive, less toxic treatment while maintaining excellent outcomes.
-
Biological factors behind different outcomes in HPV+ oropharyngeal cancer
This project looks at why some people with HPV-positive throat cancer have better or worse survival, by studying tumor biology in a large Cleveland patient group.
-
Understanding how oral high-risk HPV progresses in people with HIV to prevent oropharyngeal cancer
This study follows HIV patients at high risk for HPV-related throat cancer to understand how oral HPV infections start and change over time, with the goal of catching precancer early.
-
Biomarker-based screening to find HPV-related oropharyngeal cancer early
A non-invasive oral gargle test is being developed to detect HPV-related oropharyngeal cancer at early stages, helping people at risk catch cancer sooner.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.