Screen-and-treat cervical cancer program using HPV self-tests in Mozambique
A hybrid type III effectiveness-implementation, pragmatic intervention trial for cervical cancer screen and treat in Mozambique
This program offers women in Mozambique HPV self-testing with same-day treatment options to help prevent cervical cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11168971 on NIH RePORTER |
What this research studies
You would be offered a kit to collect your own HPV sample, which is processed to check for high-risk HPV types. If the test is positive, clinics would offer on-the-spot follow-up like a visual exam and simple treatment such as thermal ablation. The project is being rolled out across Mozambican health centers to find practical ways to deliver self-testing and immediate treatment in real-world settings. Researchers will track how well people follow up, how acceptable the approach is, and how it changes rates of precancer treatment.
Who could benefit from this research
Good fit: Women in Mozambique who are eligible for cervical cancer screening—typically adults in the screening age range and those who do not already have up-to-date screening—are the ideal candidates.
Not a fit: Women who already have invasive cervical cancer or who need specialized oncology care would not receive direct benefit from this screening-focused program.
Why it matters
Potential benefit: If successful, this could increase access to screening and timely treatment and reduce cervical cancer cases and deaths in Mozambique.
How similar studies have performed: Smaller pilot studies, including work in Mozambique, have shown that HPV self-collection is feasible and preferred, but large-scale implementation in sub-Saharan Africa is still being tested.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Moon, D. Troy — Tulane University of Louisiana
- Study coordinator: Moon, D. Troy
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.