Scaling ROSE to prevent postpartum depression for all new mothers

The ROSE Scale-Up Study: Informing a decision about ROSE as universal postpartum depression prevention

NIH-funded research Michigan State University · NIH-11127736

Seeing if offering the ROSE program to all pregnant people and new mothers helps prevent postpartum depression.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMichigan State University NIH-funded
Lab location1 site (East Lansing, United States)
Project IDNIH-11127736 on NIH RePORTER

What this research studies

You may be offered ROSE — a short, evidence-based program — as part of routine prenatal or postpartum visits at participating clinics. The project partners with healthcare and community agencies to offer ROSE to every woman and uses electronic health records and enrollment data to follow who receives the program and their outcomes. Researchers will measure postpartum depression rates, costs, feasibility, and whether universal offering reduces disparities in care. The goal is to inform whether ROSE should be routinely offered to all new mothers.

Who could benefit from this research

Good fit: Pregnant people and new mothers receiving care at participating clinics or community programs are the ideal candidates for participation.

Not a fit: People already experiencing active major depression who need treatment rather than prevention, or those not served by participating sites, may not benefit from this prevention-focused program.

Why it matters

Potential benefit: If successful, this could reduce the number of postpartum depression cases and make preventive support more widely available.

How similar studies have performed: Prior trials found ROSE prevents about half of postpartum depression cases among low-income, higher-risk women, but universal delivery to all women has not been well tested.

Where this research is happening

East Lansing, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.