SAVE-FistulaS: SelfWrap-Assisted Arteriovenous Fistula Support
Official title: SAVE-FistulaS: A Pivotal Study of SelfWrap-Assisted ArterioVEnous FistulaS
Funded at Venostent, INC. · NIH-11324593 · Data updated 2026-11-12
A new approach using SelfWrap to support AV fistulas could help people who rely on hemodialysis by making fistulas last longer and work better.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Venostent, INC. NIH-funded |
| Lab location | 1 site (Houston, UNITED STATES) |
| Project start | April 15, 2020 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,212,392 |
| NIH project number | 5R44HL151025-04 |
| Project ID | NIH-11324593 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with or at risk for end-stage kidney disease who are candidates for AV fistula creation or revision.
✕Less likely to help
Patients not undergoing AV fistula procedures or those with contraindications to the SelfWrap approach may not benefit.
What this research studies
This project focuses on AV fistulas, the connection between a patient’s artery and vein used for hemodialysis. It aims to test whether a SelfWrap-assisted technique can reduce fistula failure and improve patency, potentially lowering dialysis complications. The study will follow patients who need AVF creation or revision and monitor fistula performance, blood flow, and complication rates over time. If successful, the approach could lead to fewer procedures, better dialysis access, and improved quality of life for people with kidney failure.
Why it matters
Potential benefit: If successful, patients could have more reliable dialysis access with fewer surgeries and better long-term outcomes.
How similar studies have gone: Previous work shows high AVF failure rates; this project tests a novel wrap technique that could improve outcomes in humans.
Where this research is happening
-
Venostent, INC.
Houston, United States Active
Researchers
- Principal investigator: Boire, Timothy Charles — Venostent, INC.
- Study coordinator: Boire, Timothy Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.