SAGE LEAF 2: Online positive-emotion program to ease Alzheimer's caregiver burden

SAGE LEAF 2: An Online Self-Guided Positive Emotion Regulation Program to Reduce Alzheimer's Dementia Caregiver Burden Delivered through Caregiver-Serving Organizations

['FUNDING_SBIR_2'] · BRIGHTOUTCOME INC. · NIH-11181595

An online self-guided program that helps people caring for someone with Alzheimer's build positive-emotion skills to reduce stress and loneliness.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorBRIGHTOUTCOME INC. (nih funded)
Locations1 site (BUFFALO GROVE, UNITED STATES)
Trial IDNIH-11181595 on ClinicalTrials.gov

What this research studies

You would work through an online, self-guided program that teaches positive-emotion skills developed from an earlier facilitator-led LEAF program. The program is packaged to be offered through caregiver-serving organizations so you can join via a trusted local or national partner. Researchers will collect information from participants before and after the program about mood, caregiver burden, social connection, and well-being. The program focuses on practical activities and exercises you can do at home to increase positive feelings and cope with caregiving demands.

Who could benefit from this research

Good fit: Unpaid family members or other informal caregivers who provide care for a person living with Alzheimer's disease or another dementia.

Not a fit: People who are not caring for someone with dementia, those who prefer in-person support, or caregivers without reliable internet access may not benefit from the online program.

Why it matters

Potential benefit: If successful, this could help caregivers feel less stressed, less lonely, and more positive about their caregiving role.

How similar studies have performed: A prior facilitator-led LEAF intervention produced improvements in positive emotion, depression, and anxiety, but fully self-guided online delivery is less studied.

Where this research is happening

BUFFALO GROVE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease care giver, Alzheimer's disease caregiver

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.