NIH-funded research R01 grant

Safe South Africa: a teen-friendly program to cut HIV risk and interpersonal violence in adolescent boys

Official title: Testing the Efficacy of Safe South Africa: An Intervention to Prevent HIV Risk and Interpersonal Violence Among Adolescent Boys

Funded at American University · NIH-11387599 · Data updated 2026-11-12

A youth-focused program tests a tailored, community-based approach to reduce HIV risk and partner violence among 15- to 17-year-old boys.

More Violence research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAmerican University
NIH-funded
Lab location1 site (Washington, UNITED STATES)
Project startJuly 1, 2023
Project endApril 30, 2028
Funding year2026
Award (this year)$464,028
NIH project number5R01MH129161-04
Project IDNIH-11387599 on NIH RePORTER

Who could benefit from this research

Could help

Adolescent boys aged 15–17 who are attending school and are at risk for HIV or IPV.

Less likely to help

If a participant does not engage with the program or lacks access to the intervention delivery, benefits may be limited.

What this research studies

This project adapts an integrated HIV and IPV prevention program for adolescent boys, using social norms ideas to fit their school and peer environments. It will be tested in a global-to-U.S. context, aiming to make the content relevant and engaging for teens. The study will enroll 836 boys aged 15–17 and measure whether the intervention lowers STI incidence and reduces IPV perpetration compared with usual care.

Why it matters

Potential benefit: If successful, the program could reduce HIV risk and partner violence among adolescent boys and improve health and safety in schools and communities.

How similar studies have gone: Previous work showed the approach is acceptable and feasible; this study tests efficacy in reducing HIV risk and IPV.

Where this research is happening

  • American University
    Washington, United States
    Active

Researchers

  • Principal investigator: Kuo, Caroline Chia — American University
  • Study coordinator: Kuo, Caroline Chia

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.