Rule-based decision habits in anorexia nervosa

Rule-Based Decision-Making: A Novel Neuroeconomic Mechanism of Anorexia Nervosa Competitive Revision

NIH-funded research Virginia Commonwealth University · NIH-11298598

This project looks at whether rigid, rule-based decision habits keep people with anorexia nervosa stuck in harmful eating and behavior patterns.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVirginia Commonwealth University NIH-funded
Lab location1 site (Richmond, United States)
Project IDNIH-11298598 on NIH RePORTER

What this research studies

You would complete computer-based decision tasks (including the Web-Surf task) that measure how you make choices, and some visits may include brain imaging while you make decisions. Researchers will compare people with anorexia nervosa to people with obsessive-compulsive personality traits, obsessive-compulsive disorder, and healthy volunteers to see how decision styles differ. They will use computational decision models and brain network measures to link specific choice patterns to brain circuits. The goal is to identify the particular decision processes that help maintain rigid behaviors so future treatments can target them.

Who could benefit from this research

Good fit: Ideal candidates are people diagnosed with anorexia nervosa (including those with rigid or obsessive personality traits) who can attend in-person visits and complete computer tasks and brain imaging.

Not a fit: People without anorexia nervosa, those who are medically unstable, or those unable to undergo MRI or computerized testing may not directly benefit from participating.

Why it matters

Potential benefit: If successful, this work could point to new ways to tailor treatments that reduce rigid decision habits and help people recover from anorexia nervosa.

How similar studies have performed: Small pilot studies using the Web-Surf decision task have shown distinct decision patterns in related conditions, but applying neuroeconomic decision models to anorexia nervosa is a relatively new approach.

Where this research is happening

Richmond, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.