Robots to make treatment for collapsed vertebrae safer with less X‑ray

A Multi-robot System for Semi-automated Image-guided Vertebral Augmentation

NIH-funded research Johns Hopkins University · NIH-11308253

This project builds compact robots, image-guided software, and mixed-reality tools to help doctors treat painful collapsed vertebrae more safely, with less X‑ray exposure, and better results for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11308253 on NIH RePORTER

What this research studies

When a vertebra collapses and causes severe pain, doctors can use vertebral augmentation (VA) to stabilize the bone and relieve pain; this project focuses on making that procedure safer and more effective. The team will develop small, tool-mounted robots that work with X‑ray images and new algorithms to plan and guide the procedure automatically. They will also create closed-loop control systems and mixed-reality interfaces so clinicians can remotely actuate and verify robot actions. The goal is a more affordable, outpatient-friendly robotic solution that reduces radiation exposure, lowers complication rates, and allows advanced curved-instrument techniques.

Who could benefit from this research

Good fit: People with painful vertebral compression fractures—due to osteoporosis or cancer—who are candidates for vertebral augmentation would be the ideal participants or eventual beneficiaries.

Not a fit: People whose back pain is not caused by vertebral compression fractures or who are not eligible for vertebral augmentation (for example due to active infection or bleeding risks) are unlikely to benefit.

Why it matters

Potential benefit: If successful, the approach could reduce X‑ray exposure, lower complication rates, and improve pain relief and function after vertebral augmentation.

How similar studies have performed: Vertebral augmentation is an established pain-relief procedure and robotic guidance has aided other spine surgeries, but this compact, tool-mounted robotic approach for VA is a novel application.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.