NIH-funded research R21 grant

Robot-assisted ultrasound to guide spine surgery

Official title: Robot-assisted intraoperative ultrasound for spine image-guidance

Funded at Worcester Polytechnic Institute · NIH-11303484 · Data updated 2026-11-12

A new approach uses a small robot and ultrasound during spine operations to improve accuracy and patient outcomes.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionWorcester Polytechnic Institute
NIH-funded
Lab location1 site (Worcester, United States)
Project startJuly 15, 2026
Project endJune 30, 2028
Funding year2026
Award (this year)$368,897
NIH project number1R21AR085853-01A1
Project IDNIH-11303484 on NIH RePORTER

Who could benefit from this research

Could help

Patients undergoing open or minimally invasive spine procedures who would benefit from enhanced image-guided navigation and planning.

Less likely to help

Patients not undergoing spine surgery with image-guided navigation may not benefit.

What this research studies

This project aims to make image-guided spine surgery more reliable by pairing robot-assisted intraoperative ultrasound with automatic registration to preoperative CT scans. The team will build a level-wise registration pipeline so ultrasound can be used for both minimally invasive and open spine procedures, potentially reducing dependence on intraoperative CT. They will test the methods first in cadaver and animal models to establish ground-truth comparisons and measure accuracy and efficiency before considering clinical use.

Why it matters

Potential benefit: If successful, this work could make spine surgeries safer and more precise by improving real-time guidance with ultrasound.

How similar studies have gone: Related image-guided surgery methods have shown promise, but this project addresses a specific registration approach using intraoperative ultrasound.

Where this research is happening

  • Worcester Polytechnic Institute
    Worcester, United States
    Active

Researchers

  • Principal investigator: Ji, Songbai — Worcester Polytechnic Institute
  • Study coordinator: Ji, Songbai

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.