Risk of tuberculosis spreading from cattle to people in South India
Estimation of risk associated with zoonotic tuberculosis in South India
['FUNDING_R01'] · PENNSYLVANIA STATE UNIVERSITY, THE · NIH-11257339
This project looks at how often and how people catch tuberculosis from cattle in South India, especially through close contact and drinking unpasteurized milk.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIVERSITY, THE (nih funded) |
| Locations | 1 site (UNIVERSITY PARK, UNITED STATES) |
| Trial ID | NIH-11257339 on ClinicalTrials.gov |
What this research studies
If you live near cattle or drink raw milk in South India, the team will test animals and people for tuberculosis bacteria and compare the results. They will collect samples from cattle and from people, sequence the bacterial DNA to see whether infections match, and gather information about milk consumption and animal contact. Researchers will combine lab findings with surveys and farm observations to estimate which activities and settings raise the risk of transmission. The work is meant to identify where and how tuberculosis spills over from cattle into people so prevention can be targeted.
Who could benefit from this research
Good fit: Ideal participants are people in South India who live with or work closely with cattle or who regularly consume unpasteurized milk, such as farmers, dairy workers, and household members.
Not a fit: People in areas without bovine TB exposure, those whose TB is clearly from human-to-human spread, or people outside the study regions are unlikely to benefit directly.
Why it matters
Potential benefit: If successful, this work could help prevent TB infections from cattle by guiding testing, milk-safety, and animal-control measures that protect communities.
How similar studies have performed: Similar field sampling and genetic-testing approaches have detected zoonotic TB in other countries, but India-specific data are limited and this project seeks to fill that gap.
Where this research is happening
UNIVERSITY PARK, UNITED STATES
- PENNSYLVANIA STATE UNIVERSITY, THE — UNIVERSITY PARK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KAPUR, VIVEK — PENNSYLVANIA STATE UNIVERSITY, THE
- Study coordinator: KAPUR, VIVEK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Bovine Diseases, Cattle Diseases, Disease, Disorder