Revolutionizing limb reconstruction by combining body and machine design

Compliant Limb Reconstruction: Co-engineering Body and Machine to Revolutionize Limb Salvage

NIH-funded research University of California Los Angeles · NIH-11177267

This study is exploring new ways to help people with injured or diseased limbs move better and feel less pain by combining surgery with smart mechanical designs, aiming to create better bionic solutions for those who might otherwise need an amputation.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11177267 on NIH RePORTER

What this research studies

This research aims to restore function in limbs affected by injury or disease by integrating surgical techniques with mechanical design. It focuses on a novel approach called anatomics, which co-engineers biological and artificial components to enhance bionic performance. By understanding the flexible structures of the human body, particularly joints, the research seeks to address the challenges faced by patients with limb pathologies. The goal is to develop solutions that improve movement and reduce pain for individuals who may otherwise face amputation.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from severe limb injuries or diseases that impair joint function.

Not a fit: Patients with stable limb conditions or those who have already undergone successful limb reconstruction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to innovative treatments that restore mobility and reduce pain for patients with limb dysfunction.

How similar studies have performed: While the approach of co-engineering biological and mechanical systems is innovative, similar research has shown promise in enhancing limb function through advanced prosthetics and bionic devices.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.