Reversing cellular aging through epigenetic changes
Epigenetic Reprogramming of Cellular Age
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11026379
This study is looking at how factors in our bodies can affect how our cells age, and it’s exploring ways to help rejuvenate them, which could lead to new treatments for age-related issues that you might face as you get older.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11026379 on ClinicalTrials.gov |
What this research studies
This research investigates how systemic factors can influence the aging of cells and tissues, focusing on the potential to promote rejuvenation. The approach involves studying the effects of heterochronic parabiosis and blood exchange to understand how these factors can alter cellular aging. By examining muscle stem cells and other cell populations, the research aims to uncover the molecular mechanisms behind aging and explore epigenetic reprogramming as a means to reverse age-related changes. Patients may benefit from insights that could lead to new therapies for age-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research are individuals aged 65 and older who may be experiencing age-related health issues.
Not a fit: Patients under the age of 65 or those with conditions unrelated to aging may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that slow down or reverse the aging process in cells, improving health outcomes for older adults.
How similar studies have performed: Previous studies have shown promise in using similar approaches to influence cellular aging, suggesting potential for success in this research.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RANDO, THOMAS A. — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: RANDO, THOMAS A.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.