Restoring Vision After Cortical Blindness

Vision recovery in cortical blindness

NIH-funded research University of Rochester · NIH-11030298

This project is developing new ways to help adults who have lost their vision due to a stroke.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11030298 on NIH RePORTER

What this research studies

Stroke damage to the brain's primary visual area can cause a condition called cortical blindness, where a person loses conscious vision in part of their visual field. Currently, there are no accepted treatments to restore this vision, affecting up to half a million new cases each year. This project builds on two decades of work showing that specific visual training can help patients regain some sight. Researchers are working to improve these training methods, aiming for more effective and higher-quality vision restoration. They are also exploring why current recovery is limited, possibly due to nerve cell loss in the visual system.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 and older who have experienced cortical blindness or hemianopia due to a stroke.

Not a fit: Patients whose vision loss is not due to stroke damage in the primary visual cortex may not benefit from this specific approach.

Why it matters

Potential benefit: If successful, this work could lead to effective therapies that help adults with cortical blindness regain lost vision and significantly improve their quality of life.

How similar studies have performed: Previous work by this team has consistently shown that gaze-contingent visual training can recover some vision in chronic cortical blindness patients.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.