Restoring the Immune System After Radiation Exposure
Official title: Regeneration of the Immune System after Radiation Exposure
Funded at Albert Einstein College of Medicine · NIH-11123215 · Data updated 2026-11-12
This project looks for ways to help the body's immune system recover after someone has been exposed to radiation.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | August 18, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $582,293 |
| NIH project number | 5U01AI170032-04 |
| Project ID | NIH-11123215 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is relevant for individuals who have experienced or are at risk of acute radiation syndrome.
✕Less likely to help
Patients without radiation exposure or immune system damage from other causes would not directly benefit from this specific research.
What this research studies
When people are exposed to radiation, their immune system can be severely damaged, leading to serious health problems like bone marrow and gut failure. Current treatments mainly help with blood cell production, but the immune system itself often struggles to fully recover. This work aims to understand how the immune system tries to rebuild itself in different parts of the body, like the bone marrow and gut, after radiation exposure. By understanding these processes, we hope to find new ways to help the immune system heal more completely.
Why it matters
Potential benefit: If successful, this work could lead to new treatments that better restore the immune system for individuals affected by radiation exposure.
How similar studies have gone: Current FDA-approved treatments for radiation exposure focus on blood cell regeneration, but comprehensive immune system regeneration remains an area of active exploration.
Where this research is happening
-
Albert Einstein College of Medicine
Bronx, United States Active
Researchers
- Principal investigator: Guha, Chandan — Albert Einstein College of Medicine
- Study coordinator: Guha, Chandan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.