Restoring low-blood-sugar awareness in adults with Type 1 diabetes
The Biostatistics Research Center for the Impaired Awareness of Hypoglycemia Consortium
This project aims to use modern diabetes technology and care to help adults with Type 1 diabetes who have trouble sensing low blood sugar regain that awareness and stronger bodily responses.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project ID | NIH-11319785 on NIH RePORTER |
What this research studies
You would join a multi-center effort that uses continuous glucose monitoring and up-to-date diabetes management to reduce dangerous low-glucose episodes while keeping overall blood sugar control. The study will track time-in-range, time spent in hypoglycemia, and other glucose patterns from wearable devices, and measure how your body reacts to low blood sugar. A central biostatistics team will analyze data across all sites to understand who improves and why. Results will help shape which treatments and technologies best restore low-sugar awareness for different people.
Who could benefit from this research
Good fit: Adults (21+) with Type 1 diabetes who have impaired awareness of hypoglycemia and are willing to follow diabetes-technology based management plans are the ideal candidates.
Not a fit: Children, people with Type 2 diabetes, or adults who already reliably sense low blood sugar are unlikely to benefit from this specific project.
Why it matters
Potential benefit: If successful, this work could reduce dangerous, unrecognized low-blood-sugar episodes and lower the risk of severe events like fainting or coma for people with impaired awareness.
How similar studies have performed: Previous work shows continuous glucose monitoring and careful avoidance of hypoglycemia can sometimes restore awareness, but results vary and this consortium seeks to understand that variability.
Where this research is happening
Hershey, United States
- Pennsylvania State Univ Hershey Med Ctr — Hershey, United States (Active)
Researchers
- Principal investigator: Chinchilli, Vernon M — Pennsylvania State Univ Hershey Med Ctr
- Study coordinator: Chinchilli, Vernon M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.