Restoring Immune Health to Eliminate HIV-1

Reversing Immune Dysfunction for HIV-1 Eradication

NIH-funded research Scripps Research Institute, the · NIH-11086049

This research brings together experts to find new ways to restore the immune system in people with HIV, aiming to clear the virus from the body.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionScripps Research Institute, the NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11086049 on NIH RePORTER

What this research studies

We are exploring why the immune system struggles to fight HIV and how this allows the virus to hide. Our team will test new ideas, including how gut bacteria and body chemistry might affect immune responses against HIV. The goal is to develop treatments that can fix immune problems, making it possible to wake up hidden virus and remove it. This work could lead to a cure for HIV by helping the body fight off the infection more effectively.

Who could benefit from this research

Good fit: This research is focused on understanding and treating individuals living with HIV-1.

Not a fit: Patients who do not have HIV-1 infection would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new therapies that restore immune function and help eradicate HIV-1 from the body.

How similar studies have performed: This research will test several innovative concepts for the first time, building on existing knowledge about HIV and the immune system.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency SyndromeAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.