Restoring awareness of low blood sugar in people with type 1 diabetes

University of Minnesota Clinical Center for the Restoration of Impaired Awareness of Hypoglycemia in Type 1 Diabetes

NIH-funded research University of Minnesota · NIH-11076623

This study is for people with type 1 diabetes who sometimes don't notice when their blood sugar is low, and it will test a program that teaches them how to avoid low blood sugar and uses advanced insulin delivery systems to help them regain that awareness over a year.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11076623 on NIH RePORTER

What this research studies

This research focuses on individuals with type 1 diabetes who experience impaired awareness of hypoglycemia, which can lead to confusion or unconsciousness during low blood sugar episodes. The study aims to implement a protocol that includes education on avoiding hypoglycemia and the use of advanced insulin delivery systems over a 12-month period. Participants will be enrolled in a randomized clinical trial to assess the effectiveness of these interventions in restoring awareness of low blood sugar. The research will also explore physiological factors that may influence the restoration of awareness and develop new assessment tools for identifying impaired awareness.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with type 1 diabetes who have impaired awareness of hypoglycemia.

Not a fit: Patients who do not have type 1 diabetes or those who do not experience impaired awareness of hypoglycemia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help individuals with type 1 diabetes regain awareness of low blood sugar, improving their safety and quality of life.

How similar studies have performed: Previous research has shown promise in using educational interventions and advanced insulin delivery systems to improve glycemic control in diabetes, suggesting potential success for this approach.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.