Reproductive health and fertility in male wildland firefighters

Understanding and Communicating Reproductive Health Consequences for Male Wildland Firefighters

NIH-funded research Colorado State University · NIH-11179092

This project looks at whether wildfire smoke exposure changes sperm quality and reproductive markers in male wildland firefighters.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionColorado State University NIH-funded
Lab location1 site (Fort Collins, United States)
Project IDNIH-11179092 on NIH RePORTER

What this research studies

If you are a male wildland firefighter, this work would ask you to give semen and other samples before and after fire seasons so researchers can look for changes over time. The team will measure motile sperm counts in 100 firefighters across seasons as a direct marker of fertility. In a subgroup of 50 participants they will also analyze sperm epigenetic markers that might predict sperm quality and effects on future children. The study builds on lab animal findings suggesting smoke can change sperm and aims to see if similar changes occur in people.

Who could benefit from this research

Good fit: Ideal participants are currently active male wildland firefighters of reproductive age who can provide paired semen samples across fire seasons.

Not a fit: People who are not male wildland firefighters, are not exposed to wildfire smoke, or cannot provide the required samples and follow-up are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, the findings could clarify whether firefighting smoke harms fertility and guide protective policies, screening, and reproductive counseling for firefighters.

How similar studies have performed: Animal studies have shown smoke-related changes in sperm epigenetics, but human studies on firefighter fertility are limited, making this one of the first targeted human investigations.

Where this research is happening

Fort Collins, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.