Reproductive and Sexual Health in people with HIV
Official title: Reproductive and Sexual Health
Funded at Harvard University D/b/a Harvard School of Public Health · NIH-11416840 · Data updated 2026-11-12
This project aims to understand how stress, aging, and HIV treatment affect reproductive and sexual health in people living with HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard University D/b/a Harvard School of Public Health NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 12, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $290,799 |
| NIH project number | 5U19HD119901-02 |
| Project ID | NIH-11416840 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with HIV, including those with perinatally acquired HIV, enrolled in PHACS and with available biospecimens and data.
✕Less likely to help
Individuals without HIV or without access to PHACS data or biospecimens may not directly benefit.
What this research studies
Researchers will use existing PHACS data and biospecimens to study how long-term HIV infection and ART-related factors influence allostatic load and how this relates to pregnancy outcomes, aging of the reproductive system, and subfertility. The study will look at metabolic, inflammatory, stress, and reproductive biomarkers in previously enrolled participants, with attention to social determinants of health like neighborhood conditions, support networks, and nutrition. Using retrospective analyses and translational science approaches, they hope to identify biologic pathways that link chronic stress to adverse reproductive outcomes in young adults with HIV, including those with perinatally acquired infection. The results could guide future interventions to improve reproductive health and aging in PWH.
Why it matters
Potential benefit: Understanding these links could lead to better prevention and treatment strategies to improve reproductive health and aging for people living with HIV.
How similar studies have gone: Prior work shows links between stress, aging, and reproductive health in HIV, but this project focuses on allostatic load in aging PWH, which is a strong, but not yet fully established, approach.
Where this research is happening
-
Harvard University D/b/a Harvard School of Public Health
Boston, United States Active
Researchers
- Principal investigator: Yee, Lynn M — Harvard University D/b/a Harvard School of Public Health
- Study coordinator: Yee, Lynn M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.