Removing blood clots in patients with pulmonary embolism using catheters

Who could benefit from this research

What this research studies

This research investigates the effectiveness of catheter-directed therapy (CDT) for patients suffering from submassive pulmonary embolism (PE), a condition where blood clots block blood flow in the lungs. The study aims to compare the outcomes of patients receiving CDT against those who do not receive this treatment. By using a randomized trial design, researchers will assess improvements in patients' oxygen consumption and quality of life over time. The goal is to determine if CDT can enhance long-term cardiopulmonary health without significantly increasing the risk of bleeding.

Why it matters

Where this research is happening

• New York University School of Medicine
  New York, United States Active

Researchers

• Principal investigator: Rao, Sunil V — New York University School of Medicine
• Study coordinator: Rao, Sunil V

Related research

Other NIH-funded projects on the same topics.

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• Endovascular vortex ultrasound to treat blood clots in the lungs

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  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11448155

• Supplemental Oxygen for Pulmonary Embolism: A Mechanistic Look at How Oxygen Helps the Heart and Lungs

  This NIH grant tests how giving extra oxygen affects lung pressure and heart strain in people with acute pulmonary embolism, with supportive animal studies to understand the biology.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11401200

• Pulmonary embolism: catheter-directed clot removal for better outcomes

  This trial tests whether delivering clot-dissolving medication directly to the lungs via a catheter helps people with submassive pulmonary embolism feel better and function better, with fewer bleeding risks.

  NIH research New York University School of Medicine · New York, United States · NIH-11384861

• Pulmonary embolism treatment with catheter-directed thrombus removal versus no catheter therapy

  This study tests whether removing clot with a targeted catheter approach helps people with submassive pulmonary embolism feel better and move more easily, compared with not using catheter therapy.

  NIH research New York University School of Medicine · New York, United States · NIH-11381072

• Molecular and imaging study of blood clots and inflammation in pulmonary embolism

  A research project uses a mouse model to understand how blood clots and inflammatory cells affect pulmonary embolism and its outcomes, with the goal of better diagnosis and treatment for people with PE.

  NIH research Masonic Medical Research Laboratory, INC · Utica, United States · NIH-11333828

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.