Removing blood clots in patients with pulmonary embolism using catheters
1/2 Pulmonary Embolism: Thrombus Removal with Catheter-Directed Therapy (PE-TRACT Trial)
This study is looking at whether a special treatment called catheter-directed therapy can help people with submassive pulmonary embolism breathe better and feel healthier over time, compared to those who don’t receive this treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10929511 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of catheter-directed therapy (CDT) for patients suffering from submassive pulmonary embolism (PE), a condition where blood clots block blood flow in the lungs. The study aims to compare the outcomes of patients receiving CDT against those who do not receive this treatment. By using a randomized trial design, researchers will assess improvements in patients' oxygen consumption and quality of life over time. The goal is to determine if CDT can enhance long-term cardiopulmonary health without significantly increasing the risk of bleeding.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with submassive pulmonary embolism who exhibit right heart dysfunction but maintain normal blood pressure.
Not a fit: Patients with massive pulmonary embolism or those who do not have right heart dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with submassive pulmonary embolism, enhancing their quality of life and functional capacity.
How similar studies have performed: Previous research has shown promising results with catheter-directed therapy in similar patient populations, suggesting potential for success in this trial.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Rao, Sunil V — New York University School of Medicine
- Study coordinator: Rao, Sunil V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.