Removing blood clots in patients with pulmonary embolism using catheter therapy
2/2 Pulmonary Embolism: Thrombus Removal with Catheter-Directed Therapy (PE-TRACT Trial) –DCC
['FUNDING_OTHER'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-10928723
This study is looking at how well a special treatment called catheter-directed therapy (CDT) works for people with submassive pulmonary embolism (PE), which is when blood clots block blood flow to the lungs, and it will compare the results of those who get this treatment to those who don’t, all while aiming to help improve heart and lung health with less risk of bleeding.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10928723 on ClinicalTrials.gov |
What this research studies
This research investigates the effectiveness of catheter-directed therapy (CDT) for patients suffering from submassive pulmonary embolism (PE), a condition where blood clots block blood flow to the lungs. The study aims to compare the outcomes of patients receiving CDT against those who do not receive this treatment. By using a lower dose of thrombolytic drugs, CDT may reduce the risk of severe bleeding while still improving heart and lung function. The trial will involve up to 500 patients and will assess both short-term and long-term health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with submassive pulmonary embolism who exhibit right heart dysfunction but maintain normal blood pressure.
Not a fit: Patients with severe pulmonary embolism or those who do not have right heart dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective treatment options for patients with pulmonary embolism, improving their quality of life and functional capacity.
How similar studies have performed: Previous research has shown promising results with catheter-directed therapy in similar patient populations, indicating potential for success in this trial.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TROXEL, ANDREA B — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: TROXEL, ANDREA B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.