NIH-funded research R01 grant

Remote AI screening for early speech and swallowing changes in ALS

Official title: AI-assisted multimodal digital remote screening for bulbar ALS to support timely referral to SLP care

Funded at Sunnybrook Research Institute · NIH-11120113 · Data updated 2026-11-12

An AI-based remote audio and video tool for people with ALS to help spot early speech and swallowing changes so they can get speech-language care sooner.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSunnybrook Research Institute
NIH-funded
Lab location1 site (Toronto, Canada)
Project startJuly 20, 2018
Project endJuly 31, 2030
Funding year2025
Award (this year)$528,090
NIH project number2R01DC017291-06
Project IDNIH-11120113 on NIH RePORTER

Who could benefit from this research

Could help

People diagnosed with ALS, especially those early in their disease course or without obvious bulbar symptoms, would be the ideal candidates.

Less likely to help

People without ALS or those with already advanced bulbar impairment are unlikely to gain benefit from early remote screening.

What this research studies

This project is building an AI-based remote tool that uses short audio and video recordings you can do at home to look for early speech and swallowing (bulbar) changes common in ALS. Researchers will collect repeated recordings over time to see how practice affects speech measures and to train algorithms to detect subtle changes. They will develop and internally test clinical predictive algorithms that combine audio and video features to screen for early bulbar dysfunction and to predict future decline on established bulbar measures. The goal is an automatic remote system that flags people who need faster referral to speech-language pathology so problems are treated earlier.

Why it matters

Potential benefit: If successful, the tool could help detect bulbar problems earlier and speed up referral to speech-language pathology for timely care and management.

How similar studies have gone: Speech-analysis approaches have shown promise in ALS, but combining multimodal audio and video for remote bulbar screening and prediction is relatively new and still under development.

Where this research is happening

  • Sunnybrook Research Institute
    Toronto, Canada
    Active

Researchers

  • Principal investigator: Yunusova, Yana — Sunnybrook Research Institute
  • Study coordinator: Yunusova, Yana

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.