Remedy for Aged Muscle After Disuse Atrophy
Official title: BCCMA: Recovery of Aged Muscle After Disuse Atrophy (REMEDY): Targeting energetics and proteostasis in recovery from disuse atrophy
Funded at Oklahoma City VA Medical Center · NIH-11312599 · Data updated 2026-11-12
Aging veterans who get hospitalized often don’t fully regain muscle mass or strength after bed rest, and this project aims to help them recover faster.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma City VA Medical Center NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2029 |
| Funding year | 2027 |
| NIH project number | 5I01BX006508-02 |
| Project ID | NIH-11312599 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older Veterans at high risk of hospital-acquired weakness and disuse-related muscle loss.
✕Less likely to help
Patients without recent hospital-related muscle disuse or younger populations may see limited direct benefit.
What this research studies
This grant focuses on older veterans who experience hospital-related muscle loss. It combines lab studies to understand why aged muscles don’t regrow well with strategies to predict risk and tailor care. The team will test approaches in preclinical models, then use patient-level data to foresee who is at risk and monitor muscle health during recovery. The goal is to identify practical ways to characterize muscle disuse and support better physical function in older Veterans.
Why it matters
Potential benefit: If successful, it could lead to better recovery of muscle and function for older veterans after hospital stays.
How similar studies have gone: Previous work suggests mitochondrial and proteostatic issues contribute to poor muscle recovery in aging, with ongoing efforts to translate these findings to care.
Where this research is happening
-
Oklahoma City VA Medical Center
Oklahoma City, United States Active
Researchers
- Principal investigator: Bodine, Sue C — Oklahoma City VA Medical Center
- Study coordinator: Bodine, Sue C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.