Refining diagnostics to better detect and monitor Oropouche transmission
Official title: Refining Diagnostics for the Improved Detection, Surveillance, and study of the Transmission Dynamics of Oropouche
Funded at Asociacion Benefica Prisma · NIH-11426087 · Data updated 2026-11-12
Aimed at improving how we detect Oropouche virus infections and track how it spreads in humans, animals, and mosquitoes in endemic areas.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Asociacion Benefica Prisma NIH-funded |
| Lab location | 1 site (Lima, Peru) |
| Project start | September 21, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $693,616 |
| NIH project number | 1R01AI201194-01 |
| Project ID | NIH-11426087 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include individuals with febrile illness in OROV-endemic areas and researchers studying zoonotic transmission.
✕Less likely to help
Patients without exposure in endemic settings or without febrile illness related to OROV may not directly benefit.
What this research studies
This project will develop and apply better diagnostic tests to measure how many people are affected by Oropouche virus in real-world settings. Researchers will study non-human vertebrate hosts and local mosquito populations to understand who or what is spreading the virus. They will follow a cohort of febrile patients and use both advanced and simpler tests to map transmission dynamics in a high-risk area in Peru. The work combines human health surveillance with studies of animals and vectors to fill key gaps in knowledge. The overall goal is to inform public health actions to reduce transmission and disease burden.
Why it matters
Potential benefit: If successful, the project could lead to better, faster detection and tracking of Oropouche virus, guiding targeted interventions to protect communities.
How similar studies have gone: Previous work has shown that combining molecular and serological tests improves understanding of arbovirus transmission, though comprehensive human–vector–host studies for OROV are limited.
Where this research is happening
-
Asociacion Benefica Prisma
Lima, Peru Active
Researchers
- Principal investigator: Paredes Olortegui, Maribel — Asociacion Benefica Prisma
- Study coordinator: Paredes Olortegui, Maribel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.