Reducing unnecessary antibiotic use in children after surgery

De-Implementation of Unnecessary Surgical Antibiotic Prophylaxis in Children

NIH-funded research Washington University · NIH-10671500

This study is looking at ways to reduce the use of antibiotics in kids after certain low-risk surgeries when they aren't really needed, to help prevent problems like antibiotic resistance, and it will check how well these new approaches work in keeping kids healthy after their operations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-10671500 on NIH RePORTER

What this research studies

This research focuses on minimizing the use of antibiotics in children following low-risk surgical procedures where they are not needed. It aims to develop and test strategies to eliminate unnecessary antibiotic prophylaxis, which can lead to antibiotic resistance and other health issues. The study will assess the effectiveness of these strategies by monitoring clinical outcomes such as surgical site infections and Clostridioides difficile infections. By engaging with healthcare providers and utilizing evidence-based guidelines, the research seeks to improve antibiotic stewardship in pediatric surgery.

Who could benefit from this research

Good fit: Ideal candidates for this research are children undergoing low-risk surgical procedures who may be prescribed unnecessary antibiotics.

Not a fit: Patients undergoing high-risk surgeries or those with existing infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of antibiotic resistance and related infections in children.

How similar studies have performed: Previous research has shown that implementing antibiotic stewardship programs can effectively reduce unnecessary antibiotic use in various healthcare settings.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.