Reducing unhealthy drinking and improving mental health for people with HIV in Zambia

CHARTZ

NIH-funded research University of Alabama at Birmingham · NIH-11173881

A brief counseling program delivered by trained lay providers aims to help adults with HIV in Zambia cut down on risky drinking and improve mental health.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11173881 on NIH RePORTER

What this research studies

If you join, you'll be offered the Common Elements Treatment Approach (CETA), a package of counseling techniques delivered by trained lay providers in local clinics. The program is typically delivered in 6–12 one-on-one sessions and addresses alcohol use along with depression, trauma, and other substance problems in a single plan. This project is a hybrid effectiveness-implementation trial, so researchers will look at both how well the counseling helps people and how feasible it is for clinics to deliver it. The work focuses on adults living with HIV in Zambia where conventional brief alcohol interventions have not worked well.

Who could benefit from this research

Good fit: Adults (18+) living with HIV in Zambia who are drinking at unhealthy levels and may have co-occurring depression, trauma, or other substance use are the ideal candidates.

Not a fit: People without HIV, those not drinking at risky levels, individuals requiring specialized psychiatric or inpatient care, or people who live outside participating clinics in Zambia are unlikely to benefit or be eligible.

Why it matters

Potential benefit: If successful, this approach could help people with HIV drink less, reduce mental health symptoms, and improve adherence to HIV treatment.

How similar studies have performed: Previous randomized trials of CETA showed benefits for mental health and substance-related problems in low-resource and trauma-affected populations, but brief alcohol interventions have generally not succeeded in sub-Saharan Africa, so this specific application remains promising but not yet proven.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.