Reducing tobacco use and harm in Appalachian Kentucky

Appalachian Tobacco Regulatory Science Team (AppalTRuST)

['FUNDING_OTHER'] · UNIVERSITY OF KENTUCKY · NIH-11163562

This project looks at how new tobacco rules could change what people buy and use in rural Appalachian Kentucky to help protect local health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF KENTUCKY (nih funded)
Locations1 site (LEXINGTON, UNITED STATES)
Trial IDNIH-11163562 on ClinicalTrials.gov

What this research studies

Researchers are studying how possible FDA actions—like lowering nicotine in cigarettes or restricting flavors—might change tobacco buying and use in Appalachian Kentucky. They will use behavioral economics methods, local surveys, purchase experiments, and community outreach to see how people switch between products. The team will analyze sales, patterns of use, and how different groups in the community respond to policy changes. Local partnerships will help recruit residents and share results that could guide better rules for this region.

Who could benefit from this research

Good fit: Ideal participants are adults who live in Appalachian Kentucky and currently use cigarettes, e-cigarettes, or other tobacco products.

Not a fit: People who do not use tobacco or who live outside the Appalachian region are unlikely to get direct benefits from this project.

Why it matters

Potential benefit: If successful, this work could help shape regulations that lower smoking and nicotine addiction in Appalachian communities and reduce tobacco-related illness.

How similar studies have performed: Other studies using behavioral economics and policy simulations have successfully predicted changes in tobacco use and informed regulations, though effects can differ by community and product.

Where this research is happening

LEXINGTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.