Reducing the spread of typhoidal Salmonella in the Indo-Pacific region.
Official title: Modeling the Impact of Interventions to Reduce Typhoidal Salmonella Transmission in the Indo-Pacific.
Funded at Stanford University · NIH-10863413 · Data updated 2026-11-12
This study is looking at how to help keep kids under 11 safe from typhoidal Salmonella by improving water, sanitation, and hygiene in communities in Indonesia and Fiji, especially in places affected by climate change.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 11, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $169,035 |
| NIH project number | 1K23AI182452-01 |
| Project ID | NIH-10863413 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children under the age of 11 living in areas with high rates of typhoidal Salmonella infections.
✕Less likely to help
Patients who do not live in the Indo-Pacific region or are over the age of 11 may not benefit from this research.
What this research studies
This research investigates how to effectively reduce the transmission of typhoidal Salmonella, particularly in children under 11 years old, in the Indo-Pacific region. It focuses on improving water, sanitation, and hygiene (WASH) infrastructure to decrease the risk of infection, especially in areas vulnerable to climate change. The study involves a community-level trial in urban settlements in Indonesia and Fiji, assessing the impact of these interventions on reducing disease burden. By evaluating the effectiveness of these strategies, the research aims to provide actionable insights for public health improvements.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of typhoidal Salmonella infections in vulnerable populations, particularly children.
How similar studies have gone: Previous research has shown that community-level WASH interventions can effectively reduce disease transmission, indicating a promising approach for this study.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Hoffman, Seth Ari Sim-Son — Stanford University
- Study coordinator: Hoffman, Seth Ari Sim-Son
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.