Reducing stress-related drinking and improving HIV self-care for young people

Defining intervention targets along pathways from cumulative stress and trauma to alcohol and HIV self-management among young people living with HIV (Project DEFINE)

NIH-funded research Florida State University · NIH-11173780

This project looks at ways to help young people with HIV manage stress, sleep, emotions, and decision-making so they drink less and stick with HIV care.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionFlorida State University NIH-funded
Lab location1 site (Tallahassee, United States)
Project IDNIH-11173780 on NIH RePORTER

What this research studies

You would be asked about your life stress, trauma, alcohol use, sleep, and how you handle emotions and decisions. The team will combine surveys, sleep measures, cognitive tests, and medical records to map how stress leads to drinking and poorer HIV self-care. They aim to find specific, changeable points (like sleep or emotion regulation) where new supports could help. Results will guide future programs tailored to the needs of young people living with HIV.

Who could benefit from this research

Good fit: Young people living with HIV—especially adolescents and young adults who use alcohol or have a history of stress or trauma—are the ideal candidates for this work.

Not a fit: Older adults with HIV or people without alcohol use or significant stress/trauma are less likely to benefit directly from these findings.

Why it matters

Potential benefit: If successful, this work could lead to targeted programs that reduce hazardous drinking and improve medication adherence and viral control among young people with HIV.

How similar studies have performed: Prior research links stress, sleep, emotion regulation, and substance use to HIV outcomes, but combining these factors in a developmentally focused approach for young people is relatively new.

Where this research is happening

Tallahassee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.