Reducing stigma to improve HIV care for transgender women

Ssimusango: Multi-level intervention for intersectional stigma reduction to improve HIV outcomes for transgender women

NIH-funded research Infectious Diseases Institute · NIH-11095881

This study is looking to help transgender women in sub-Saharan Africa by testing new ways to reduce stigma and improve access to HIV care and prevention, so they can stay healthy and feel supported.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionInfectious Diseases Institute NIH-funded
Lab location1 site (Kampala, Uganda)
Project IDNIH-11095881 on NIH RePORTER

What this research studies

This research focuses on transgender women in sub-Saharan Africa, who face a significantly higher risk of HIV infection due to intersectional stigma and discrimination. The project aims to adapt and implement two evidence-based interventions that target stigma at both the health facility and individual levels. By combining the Health Policy Plus Total Facility Approach and the HIV Education, Empathy and Empowerment program, the study seeks to improve engagement in HIV care and adherence to preventive treatments like PrEP. Participants will be involved in a randomized controlled trial to assess the effectiveness of this multi-level intervention.

Who could benefit from this research

Good fit: Ideal candidates for this research are transgender women living in sub-Saharan Africa who are at risk for HIV.

Not a fit: Patients who do not identify as transgender women or who are not at risk for HIV may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved HIV prevention and treatment outcomes for transgender women.

How similar studies have performed: Previous research has shown success with similar stigma reduction interventions, but this specific adaptation for transgender women in sub-Saharan Africa is novel.

Where this research is happening

Kampala, Uganda

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.