Reducing organ dysfunction in older patients after trauma.
Attenuation of Multiorgan Dysfunction after Shock in the Aged
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-11083118
This study is looking at how to help older patients recover better after experiencing trauma or shock by blocking harmful digestive enzymes that can leak into their blood and affect their organs.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-11083118 on ClinicalTrials.gov |
What this research studies
This research investigates how to prevent multiple organ dysfunction in older patients who experience trauma or shock. It focuses on the role of digestive enzymes that leak into the bloodstream and cause harm to various organs. By blocking these enzymes, the study aims to improve recovery outcomes for aged individuals. The approach is based on previous successful trials in younger patients and seeks to address the unique challenges faced by older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who have experienced trauma or shock.
Not a fit: Patients who are younger or do not have a history of trauma or shock may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery and quality of life for older patients after traumatic events.
How similar studies have performed: Previous studies have shown success in younger populations using similar approaches, indicating potential for effectiveness in older patients.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHMID-SCHOENBEIN, GEERT W. — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: SCHMID-SCHOENBEIN, GEERT W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury