Reducing opioid use for managing pain after surgery

Opiod Analgesic Reduction Study (OARS): Managing Acute Post-Operative Surgical Pain

['FUNDING_OTHER'] · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · NIH-10670330

This study is looking at how to manage pain after wisdom tooth surgery without using opioids, by comparing a mix of non-opioid pain relievers to regular opioid painkillers, to see which option helps patients feel better with fewer side effects.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorRUTGERS BIOMEDICAL AND HEALTH SCIENCES (nih funded)
Locations1 site (Newark, UNITED STATES)
Trial IDNIH-10670330 on ClinicalTrials.gov

What this research studies

This research investigates how to effectively manage acute post-operative pain without relying on opioid medications. It involves a clinical trial where patients undergoing third molar extractions will be randomly assigned to receive either a combination of non-opioid pain relievers or the commonly prescribed opioid analgesic. The study aims to compare pain levels, side effects, patient satisfaction, and daily functioning between the two groups. By focusing on a common surgical procedure, the findings could provide valuable insights for pain management practices.

Who could benefit from this research

Good fit: Ideal candidates for this research are young adults undergoing third molar extractions who require pain management post-surgery.

Not a fit: Patients who are not undergoing surgical procedures or those with chronic pain conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the reliance on opioids for pain management, thereby lowering the risk of addiction and overdose.

How similar studies have performed: Previous research has shown that non-opioid analgesics can be effective for managing post-operative pain, suggesting that this approach may yield positive results.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.