Reducing lung cancer differences in Native Hawaiian communities
Project 2: Mitigating Population Differences in Lung Cancer among Native Hawaiians: A Population-Based Approach to Enhance Prevention and Elucidate Lung Tumor Biologyy
This project looks at why Native Hawaiians have higher lung cancer rates and works to improve early detection and prevention for Native Hawaiian adults.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Hawaii at Manoa NIH-funded |
| Lab location | 1 site (Honolulu, United States) |
| Project ID | NIH-11184184 on NIH RePORTER |
What this research studies
This effort combines population data, tumor biology, and screening information to understand why Native Hawaiians face higher lung cancer risk and worse early-stage survival. Researchers will analyze genetic and epigenetic markers, tobacco-related biomarkers, and tumor characteristics using samples and data from existing cohorts. The team will also examine low-dose CT screening uptake in Hawaiʻi and barriers that limit early diagnosis. Results are intended to inform tailored prevention, outreach, and earlier detection efforts for Native Hawaiian communities.
Who could benefit from this research
Good fit: Native Hawaiian adults, especially those with a history of smoking or who are otherwise at high risk for lung cancer, are the primary group this work is meant to help.
Not a fit: People who are not Native Hawaiian or who already have advanced-stage lung cancer may be less likely to benefit directly from the early-detection and prevention focus of this project.
Why it matters
Potential benefit: If successful, the work could lead to better early detection and targeted prevention strategies that reduce lung cancer deaths among Native Hawaiians.
How similar studies have performed: Low-dose CT screening has been shown in other trials to reduce lung cancer deaths, but combining population genetics, tumor biology, and targeted screening outreach for Native Hawaiians is relatively new.
Where this research is happening
Honolulu, United States
- University of Hawaii at Manoa — Honolulu, United States (Active)
Researchers
- Principal investigator: Park, Sungshim Lani — University of Hawaii at Manoa
- Study coordinator: Park, Sungshim Lani
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.