Reducing liver cancer risk in patients with metabolic syndrome
Prevention of Hepatocellular Carcinoma Related to Metabolic Syndrome
This study is looking to help people at risk of liver cancer by finding out what factors increase that risk and how to better prevent it, and it involves patients sharing samples and information to improve our understanding.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10874531 on NIH RePORTER |
What this research studies
This research focuses on understanding and preventing hepatocellular carcinoma (HCC), a rapidly increasing cause of cancer deaths linked to metabolic syndrome and fatty liver disease. By analyzing a large cohort of patients with cirrhosis, the study aims to identify risk factors and develop predictive models for HCC. The research will utilize advanced techniques to assess metabolic traits and biomarkers, ultimately seeking to improve surveillance and prevention strategies for at-risk individuals. Patients may be involved in providing biospecimens and data to help refine these predictive algorithms.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with metabolic dysfunction-associated fatty liver disease and cirrhosis.
Not a fit: Patients without metabolic syndrome or those who do not have cirrhosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly lower the incidence of liver cancer in individuals with metabolic syndrome.
How similar studies have performed: Previous research has shown promise in using risk stratification models for liver disease, indicating potential success for this approach.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: El-Serag, Hashem B — Baylor College of Medicine
- Study coordinator: El-Serag, Hashem B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.