Reducing high insulin levels and insulin resistance in type 1 diabetes
Reducing Hyperinsulinemia and Insulin Resistance in Type 1 Diabetes Using Adjunctive Therapies
This study is looking at how combining different treatments can help people with type 1 diabetes lower their insulin levels and improve how their bodies respond to insulin, all while keeping an eye on heart health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11079590 on NIH RePORTER |
What this research studies
This research investigates how combination therapies can help lower high insulin levels and improve insulin sensitivity in individuals with type 1 diabetes. By using a double-blind, placebo-controlled crossover approach, participants will receive both the new treatment and a placebo in alternating phases. The goal is to understand how these therapies can reduce the risk of cardiovascular disease, which is a significant concern for people with type 1 diabetes. Patients will be closely monitored to assess changes in insulin levels and tissue response.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who experience high insulin levels and insulin resistance.
Not a fit: Patients who do not have type 1 diabetes or those who are not experiencing issues with insulin levels may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management of insulin levels and reduced cardiovascular risks for patients with type 1 diabetes.
How similar studies have performed: Previous research has shown promise in using adjunctive therapies to manage insulin levels, indicating that this approach may be effective.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Boeder, Schafer Cale — University of California, San Diego
- Study coordinator: Boeder, Schafer Cale
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.