Reducing heart disease caused by radiation exposure through aging prevention
Official title: Mitigating radiation-induced cardiovascular disease by inhibiting premature aging
Funded at University of Tx Md Anderson Can Ctr · NIH-10857261 · Data updated 2026-11-12
This study is looking for ways to help people who have been exposed to radiation avoid heart problems by slowing down the aging processes in their bodies, and it will involve patients trying out new treatments to see how well they work.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | July 1, 2020 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $495,268 |
| NIH project number | 5U01AI156921-05 |
| Project ID | NIH-10857261 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced radiation exposure and are at risk for cardiovascular diseases.
✕Less likely to help
Patients who have not been exposed to radiation or do not have cardiovascular disease may not benefit from this research.
What this research studies
This research investigates how to prevent cardiovascular diseases that may arise from radiation exposure by targeting the mechanisms of premature aging. The approach focuses on identifying and inhibiting the biological processes that lead to accelerated aging in patients who have been exposed to radiation. By utilizing innovative therapies, the research aims to mitigate the adverse cardiovascular effects associated with radiation, potentially improving heart health in affected individuals. Patients may be involved in trials that test these new interventions to see how effectively they can protect against heart disease.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of heart disease in patients exposed to radiation.
How similar studies have gone: While the specific approach of mitigating radiation-induced cardiovascular disease through aging prevention is novel, there have been successful studies in related areas of radiation mitigation and cardiovascular health.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Abe, Jun-Ichi — University of Tx Md Anderson Can Ctr
- Study coordinator: Abe, Jun-Ichi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.