Reducing health risks from sitting too much
Official title: Stand Up for Your Health: A Randomized Study
Funded at Medical College of Wisconsin · NIH-11014337 · Data updated 2026-11-12
This study is looking at how sitting too much can affect your health, especially for people at risk of type 2 diabetes and heart disease, and it will see if using sit-stand desks can help improve health by reducing sitting time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $523,119 |
| NIH project number | 5R01HL162888-03 |
| Project ID | NIH-11014337 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have sedentary jobs and may be at risk for metabolic disorders.
✕Less likely to help
Patients who are already highly active or those with severe mobility limitations may not benefit from this research.
What this research studies
This research investigates the impact of sedentary behavior on health, particularly focusing on how prolonged sitting can lead to conditions like type 2 diabetes and cardiovascular disease. The study will involve participants using sit-stand desks to reduce their sitting time and monitor changes in their health markers, such as insulin resistance and vascular function. By comparing the health outcomes of those who use sit-stand desks against those who continue with traditional desks, the research aims to provide insights into effective strategies for improving health in sedentary individuals.
Why it matters
Potential benefit: If successful, this research could lead to practical interventions that significantly reduce the risk of chronic diseases associated with sedentary lifestyles.
How similar studies have gone: Previous studies have shown promising results in reducing health risks associated with sedentary behavior through interventions like sit-stand desks.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: Kulinski, Jacquelyn P — Medical College of Wisconsin
- Study coordinator: Kulinski, Jacquelyn P
Related research
Other NIH-funded projects on the same topics.
-
Finding a cure for sickle cell disease
The Cure Sickle Cell Initiative is bringing together patients, families, and caregivers to work together on finding a cure for sickle cell disease using safe genetic therapies, with the goal of improving lives and speeding up the development of new treatments.
-
A portable device to measure radiation dose and exposure uniformity after a large radiation event
A field-ready, nail-based device uses advanced spectroscopy and smart software to quickly estimate how much radiation a person has received and how evenly they were exposed, within minutes.
-
Ethics of Engaging Patient Groups in Drug Development for Rare Diseases
This grant asks how patient and family groups can ethically help shape rare-disease drug development from idea to market, with input from patients, families, doctors, and researchers.
-
Renovation of the Biophysics Resources at MCW
This grant funds upgrading a core biophysics facility at the Medical College of Wisconsin to support advanced research in human biology.
-
Cure Sickle Cell: Advancing Gene Therapies for Sickle Cell Disease
A national initiative to move safer genetic therapies for sickle cell disease forward with patient, caregiver, and advocate involvement.
-
Health insurance transitions for older adults with HIV on Medicare
Older adults with HIV face complex Medicare coverage that can affect access to HIV treatment and care.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.