Reducing fracture risk in patients with Parkinson's disease
Official title: Prevention of Fractures in Patients with Parkinson's Disease
Funded at California Pacific Med Ctr Res Institute · NIH-10863965 · Data updated 2026-11-12
This study is looking at ways to help people with Parkinson's disease avoid fractures, since they often fall more and are at greater risk; it will test if vitamin D and other treatments can make a difference in keeping them healthy and safe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California Pacific Med Ctr Res Institute NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2018 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $3,135,800 |
| NIH project number | 5R01AG059417-05 |
| Project ID | NIH-10863965 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 65 or older with Parkinson's disease who are at high risk for fractures.
✕Less likely to help
Patients with Parkinson's disease who are younger than 65 or those without a significant risk of fractures may not benefit from this research.
What this research studies
This research investigates how to prevent fractures in patients with Parkinson's disease, who are at a significantly higher risk of fractures due to frequent falls. The study aims to address barriers that prevent these patients from receiving effective osteoporosis treatments, including lack of evidence for their effectiveness in this population and challenges related to medical visits and medication adherence. By conducting a randomized trial, the research will explore the impact of vitamin D supplementation and other interventions on fracture risk and overall health outcomes for these patients.
Why it matters
Potential benefit: If successful, this research could lead to improved fracture prevention strategies for patients with Parkinson's disease, enhancing their quality of life and reducing mortality associated with fractures.
How similar studies have gone: Previous research has shown that addressing barriers to osteoporosis treatment can improve outcomes, but this specific approach in Parkinson's disease is relatively novel.
Where this research is happening
-
California Pacific Med Ctr Res Institute
San Francisco, United States Active
Researchers
- Principal investigator: Cummings, Steven Ron — California Pacific Med Ctr Res Institute
- Study coordinator: Cummings, Steven Ron
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.