Reducing emotional distress to help adults with type 1 diabetes

ACT1VATE: Addressing Emotional Distress to Improve Outcomes among Diverse Adults with Type 1 Diabetes

NIH-funded research Scripps Health · NIH-10896294

This project compares adding a psychological program called ACT1VATE to standard diabetes education for adults with type 1 diabetes who have high emotional distress and trouble controlling their blood sugar.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionScripps Health NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10896294 on NIH RePORTER

What this research studies

You would join a large randomized trial of about 484 adults with poorly controlled type 1 diabetes and significant diabetes-related emotional distress. Everyone receives standard one-on-one diabetes education from a certified diabetes educator, then is randomly assigned to five telemedicine group sessions of either traditional support groups or the ACT1VATE psychological program delivered by a behavioral health provider embedded in the diabetes clinic. The study team will use Scripps electronic health records to find eligible patients and to track changes in blood sugar control over time. The project looks at whether adding ACT1VATE to usual education helps people manage diabetes better and feel less distressed.

Who could benefit from this research

Good fit: Adults (approximately 21 years and older) with type 1 diabetes, poor glycemic control, and significant diabetes distress who receive care at Scripps and can join telemedicine group sessions are the ideal candidates.

Not a fit: People with type 2 diabetes, those with well-controlled type 1 diabetes and little distress, minors, or those unable to access Scripps care or telemedicine sessions are unlikely to benefit from this project.

Why it matters

Potential benefit: If successful, this approach could reduce diabetes-related emotional distress and improve blood sugar control for adults with type 1 diabetes.

How similar studies have performed: Some smaller psychological programs have shown promise for reducing diabetes distress, but combining an ACT-style intervention with standard diabetes education in a large randomized trial like this is relatively new.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brittle Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.