Reducing brain inflammation and dysfunction in people with HIV
Suppression of Pathological Spontaneous Cortical Dynamics and Inflammation in NeuroHIV
This study is looking at how HIV can impact brain health and thinking skills, even in people whose virus levels are under control, and it aims to find ways to help improve brain function, including exploring the use of cannabinoids.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Father Flanagan's Boys' Home NIH-funded |
| Lab location | 1 site (Boys Town, United States) |
| Project ID | NIH-11013310 on NIH RePORTER |
What this research studies
This research investigates how HIV affects brain function and inflammation, particularly focusing on cognitive impairments that can arise even in individuals who are virally suppressed. The study aims to understand the underlying mechanisms of these cognitive issues by examining brain activity and inflammation pathways. Researchers will explore potential therapeutic options, including cannabinoids, to alleviate these neurological complications. By utilizing advanced neuroimaging techniques, the project seeks to identify new ways to improve brain health in people living with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are living with HIV and may be experiencing cognitive impairments.
Not a fit: Patients who are not living with HIV or those who do not exhibit any cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function and overall brain health for individuals living with HIV.
How similar studies have performed: While there is ongoing research into HIV-related cognitive impairments, this specific approach exploring cannabinoids as a treatment is relatively novel and has not been extensively tested.
Where this research is happening
Boys Town, United States
- Father Flanagan's Boys' Home — Boys Town, United States (Active)
Researchers
- Principal investigator: Wilson, Tony W — Father Flanagan's Boys' Home
- Study coordinator: Wilson, Tony W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.