Reducing blood sugar spikes to treat early type 2 diabetes

Treating early type 2 diabetes by reducing postprandial glucose excursions: A paradigm shift in lifestyle modification

NIH-funded research University of Virginia · NIH-11113804

This study is looking for 200 adults who have just been diagnosed with type 2 diabetes to try a new way to manage their blood sugar after meals, using a home program that could be easier and cheaper than taking medication.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia NIH-funded
Lab location1 site (Charlottesville, United States)
Project IDNIH-11113804 on NIH RePORTER

What this research studies

This research investigates a new approach to managing early type 2 diabetes by focusing on reducing spikes in blood sugar after meals. It aims to provide a lifestyle intervention that is more sustainable and less expensive than traditional medication regimens. The study will involve 200 adults who have recently been diagnosed with type 2 diabetes and have not yet started medication, allowing them to participate in a self-administered program from home. Participants will be randomized to receive either individualized medication management or a program designed to minimize post-meal blood glucose excursions.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who have recently been diagnosed with type 2 diabetes and have not yet begun taking diabetes medication.

Not a fit: Patients who have been diagnosed with type 2 diabetes for an extended period or those already on diabetes medication may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and manageable treatment options for individuals with early type 2 diabetes.

How similar studies have performed: Previous research has shown promising results with similar lifestyle interventions, indicating potential for success in this approach.

Where this research is happening

Charlottesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.