Reducing arsenic and uranium in Northern Plains drinking water

Columbia University and Northern Plains Partnership for the Superfund Research Program

['FUNDING_OTHER'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11124894

This partnership measures arsenic and uranium in well water and urine to help protect Tribal communities in the Northern Plains from heart-related harms.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCOLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11124894 on ClinicalTrials.gov

What this research studies

If you join, researchers will test private wells and rural water systems and collect urine samples to measure arsenic and uranium levels near tribal communities in North and South Dakota. They will build household-level maps of groundwater contamination using local knowledge, public data, and new water chemistry measurements. Isotope tests will trace where metals come from and how they move, while health data will look for links between exposures and heart problems. The team will also pilot and recommend household or community water treatments to reduce exposure.

Who could benefit from this research

Good fit: Adults living on Northern Plains tribal lands or nearby rural areas who use private wells or rural water systems and are concerned about metal exposure or heart disease are ideal candidates.

Not a fit: People who live outside the Northern Plains tribal areas or who receive treated municipal water are unlikely to receive direct benefits from this project.

Why it matters

Potential benefit: If successful, the work could find contaminated water sources and support fixes that lower metal exposure and reduce cardiovascular risk in affected communities.

How similar studies have performed: Previous regional work showed elevated arsenic and uranium in urine and links to heart disease, but combining household mapping, isotope tracing, health measures, and remediation is relatively new.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cardiac Diseases, Cardiac Disorders, Cardiometabolic Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.