REDUCE-HIV: Making deprescribing in older adults with HIV easier and more accepted
Official title: REDUCE-HIV: Research to Enhance Deprescribing and Uptake of Clinical Evidence in Older Adults With HIV
Funded at Texas Southern University · NIH-11470442 · Data updated 2026-11-12
A patient-friendly plan to help older adults living with HIV safely reduce medicines they may not need anymore.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Southern University NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 15, 2026 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $166,288 |
| NIH project number | 1R16AG105063-01 |
| Project ID | NIH-11470442 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults aged 21 and older living with HIV who are receiving care and have complex or potentially inappropriate medication regimens.
✕Less likely to help
Patients with minimal or no polypharmacy and stable regimens may see little direct benefit.
What this research studies
Older adults with HIV often take many medications, which can lead to interactions, side effects, and hospital visits. This project will design and test a practical, doctor-friendly workflow to help deprescribe in HIV care settings. It focuses on real-world use with providers and patients, aiming to fit into busy clinics and shared decision-making. If successful, it could make it easier to stop unnecessary medicines while keeping everyone safe and well.
Why it matters
Potential benefit: If successful, the deprescribing workflow could reduce adverse drug events and improve quality of life for older adults with HIV.
How similar studies have gone: Previous research shows deprescribing can improve safety in older adults, but it has not been systematically applied in HIV care settings.
Where this research is happening
-
Texas Southern University
Houston, United States Active
Researchers
- Principal investigator: Wang, Hongmei — Texas Southern University
- Study coordinator: Wang, Hongmei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.